As expected, Scott Satterfield and the Louisville Cardinals will be massive underdogs on Saturday afternoon when they host the defending national champions.
Per VegasInsider.com Louisville opened as 21.5 point underdogs to Clemson.
With a 62-59 victory over Wake Forest the Cards have improved to 4-2 on the year and also 4-2 against the spread.
Clemson is still unbeaten, but has dropped to No. 3 in the AP Poll after starting the season at No. 1. Voters are likely still wanting to see more out of Clemson following their scare from North Carolina a couple weeks ago.
The Tigers bounced back off the bye week with 45-14 beat-down of Florida State. Clemson is 4-2 against the spread in 2019.
Per VegasInsider.com the total is set at 61. I expected it to be a little higher considering Louisville has scored 103 points in their last two games and points are never a problem for Clemson.<